Stages of Zubsolv® Treatment
Zubsolv® treatment typically follows a 3-step process designed to keep you safe, supported, and set up for long-term success.
1. Pre-treatment Evaluation
Before starting Zubsolv®, our providers will meet with you to review your health history, current or past substance use, and any previous experience with medications like Suboxone® or methadone. This is your opportunity to ask questions, talk through concerns, and share what’s worked—or hasn’t worked—for you in the past.
We’ll also discuss where you are in the recovery process. If you’ve been using opioids recently, you’ll need to stop before starting Zubsolv®. Our team will help you time your last dose safely so you can start treatment without complications.
2. Starting Zubsolv®
Zubsolv® treatment begins when you take your first dose. To start safely, you’ll need to be in mild to moderate opioid withdrawal. This usually occurs about 24 to 48 hours after your last opioid use, though it varies depending on the type of opioid. Patients who have been long-time fentanyl users may need to wait longer than those who are taking prescription opioids.
If you’ve already been off opioids for several days, weeks, or even longer, you can still start Zubsolv®. In fact, induction may be smoother since your body is already clear of opioids. Zubsolv® is often used as a maintenance medication to help prevent relapse and reduce cravings in individuals who have completed detox but still need support.
Why Do You Need to Be in Withdrawal Before Starting?
Zubsolv® contains buprenorphine, a medication that binds strongly to opioid receptors in the brain. If opioids are still active in your system, taking Zubsolv® too early can displace them suddenly and trigger precipitated withdrawal—a fast, intense wave of symptoms that feels worse than typical withdrawal.
That’s why our team carefully guides you through the timing of your induction, ensuring you’re in the right stage of withdrawal before your first dose. Our goal is to make your transition into treatment as safe and comfortable as possible.
3. Maintenance Phase
Once you’re stabilized on a dose that works for you, you’ll enter the maintenance phase. You’ll take Zubsolv® once or twice a day and continue regular check-ins with your provider.
At MATClinics, we pair medication with behavioral therapy and counseling to help you work through the emotional, psychological, and lifestyle challenges that come with recovery. This combined approach helps reduce the risk of relapse and supports real, lasting change.
